A gene regulatory network is a set of genes, or parts of genes, that interact with each other to control a specific cell function. Gene regulatory networks are important in development, ...
Small-molecule degraders for oncogenic KRAS G12C and pan-KRAS mutations This work develops DJX-A-KM, a small-molecule KRASG12C degrader that recruits E3 ligase FBXO28 via dual covalent binding, ...
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