FcεRI is a multimeric immune Fc receptor that binds IgE with high affinity. It has a tetrameric structure on the surface of mast cells and basophils, consisting of one IgE-binding α-chain, one β-chain ...
The nuclear factor (NF)-κB, inhibitor of NF-κB (IκB) and IκB kinase (IKK) pathway is activated in response to various stimuli in many cell types. NF-κB is activated by many mechanisms, including the ...
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