Gene amplifications and deletions frequently have pathogenetic roles in cancer. 30,000 radiation-hybrid mapped cDNAs provide a genomic resource to map these lesions with high resolution. We developed ...
We have generated transgenic mice carrying targeted deletions of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) gene. These animals offer the unique opportunity to gain insights into ...
Tiny organisms on the ground—bacteria and fungi—have a "superpower" that allows them to reach up into the atmosphere and pull ...
An interdisciplinary research team led by Dr. Elisha Krieg at the Leibniz Institute of Polymer Research Dresden (IPF) has ...
The work demonstrates the power of ancient DNA to illuminate human biology and medicine in addition to history. A massive ...
Mayo Clinic scientists are exploring an unusual but promising strategy to treat one of the deadliest bile duct cancers by turning milk into a microscopic delivery system for gene therapy. Their work ...
BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...
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