Gene amplifications and deletions frequently have pathogenetic roles in cancer. 30,000 radiation-hybrid mapped cDNAs provide a genomic resource to map these lesions with high resolution. We developed ...
We have generated transgenic mice carrying targeted deletions of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) gene. These animals offer the unique opportunity to gain insights into ...
An interdisciplinary research team led by Dr. Elisha Krieg at the Leibniz Institute of Polymer Research Dresden (IPF) has ...
The results are transforming how scholars understand human history. By analysing parchment, researchers are uncovering ...
Tiny organisms on the ground—bacteria and fungi—have a "superpower" that allows them to reach up into the atmosphere and pull ...
Scientists are finding ways to merge biology with electronics, unlocking new possibilities for data storage and computing.
The work demonstrates the power of ancient DNA to illuminate human biology and medicine in addition to history. A massive ...
Next-generation sequencing (NGS) workflows depend on reliable sample preparation and rigorous quality control to deliver consistent results. Yet degraded or fragmented genomic DNA can undermine ...
BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...
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