Explore how advances in accuracy, throughput and cost are making long-read sequencing more accessible at scale.

During a live event, Shaji Kumar, MD, discussed when talquetamab can be sequenced in multiple myeloma as an alternative to targeting BCMA in consecutive lines. Patients with relapsed/refractory ...

Abstract: Multiple Sequence Alignment (MSA) is a fundamental challenge in bioinformatics, forming the basis for addressing numerous computational biology problems, e.g., protein structure prediction ...

Factoring out nucleotide-level mutation biases from antibody language models dramatically improves prediction of functional mutation effects while reducing computational cost by orders of magnitude.

This is read by an automated voice. Please report any issues or inconsistencies here. Ryan Coogler was deep into writing “Sinners” when he realized the movie was missing something: He needed a moment ...

i-Motifs (iMs) are cytosine-rich, four-stranded DNA structures with emerging roles in gene regulation and genome stability. Despite their biological relevance, genome-wide prediction of iM-forming ...

The EMBL File Format Converter is a specialized tool that converts biological sequence data from the EMBL format to various standard formats. It streamlines bioinformatics workflows by accurately ...

A command-line tool for detecting and extracting single homeologous polymorphisms (SHPs) from the subgenomes of allopolyploid species. This tool integrates three main algorithms, WGA, VCF2ALIGNMENT ...

Our STOCKHOLM File Format Converter is a specialized bioinformatics utility designed to improve interoperability among multiple sequence alignments (MSAs). This tool expertly converts alignments from ...

ABSTRACT: In malaria-endemic areas, the relatively high probability of hemoglobinopathies, especially sickle cell disease, raises important questions regarding the evolutionary interactions between ...