Objectives The objective of our study was to assess the benefits and harms of tramadol vs placebo in adults with chronic pain. Design The research method was a systematic review of randomised clinical ...

In a single experiment, scientists can decipher the entire genomes of many patient samples, animal models, or cultured cells. To fully realize the potential to study biology at this unprecedented ...

This illustration demonstrates how metapipeline-DNA processes raw genome sequencing data. It begins by aligning the sequence of DNA base pairs to a reference genome. Then produces sets of detected ...

Objective To synthesise meta-analytic outcomes from randomised controlled trials examining exercise effects on depression and anxiety across all population groups, including children and adults with ...

Background Patient complaints provide a complementary lens on surgical safety, yet prior analyses have been small and specialty specific. We aimed to characterise themes, perioperative processes, ...

Neuromorphic circuits operate by comparing fluctuating signals to thresholds. This operation underpins sensing and computation in both neuromorphic architectures and biological nervous systems.

Background Hypertrophic cardiomyopathy (HCM) is a leading cause of sudden cardiac death (SCD) among young individuals and athletes. Despite increasing evidence supporting exercise, uncertainty remains ...

The relentless pursuit of higher performance and greater functionality has propelled the semiconductor industry through several transformative eras. The most recent shift is from traditional ...

Background Acute heart failure (AHF) is a severe clinical syndrome associated with high morbidity and mortality. Effective management of congestion is a primary treatment goal and often requires ...

Introduction: Patients with diabetes mellitus are at increased risk of cardiovascular events such as myocardial infarction, stroke, and cardiovascular death. While aspirin’s role in secondary ...